Current Problems in Diagnostic Radiology
Volume 38, Issue 3 , Pages 135-143 , May 2009

Radiofrequency and Microwave Ablation of the Liver, Lung, Kidney, and Bone: What Are the Differences?

  • Christopher L. Brace, PhD

      Affiliations

    • Corresponding Author InformationReprint requests: Christopher L. Brace, PhD, University of Wisconsin, Department of Radiology, Clinical Sciences Center, E1/322, 600 Highland Ave., Madison, WI 53792-3252

References 

  1. Lencioni R, Cioni D, Crocetti L, et al. Early-stage hepatocellular carcinoma in patients with cirrhosis: Long-term results of percutaneous image-guided radiofrequency ablation. Radiology. 2005;234:961–967
  2. Solbiati L, Tiziana I, Michela B, et al. Radiofrequency ablation of liver metastases of colorectal origin with intention to treat: Local response rate and long-term survival over 7-year follow-up. Radiological Society of North America Annual Meeting 2006;
  3. Rose SC, Thistlethwaite PA, Sewell PE, et al. Lung cancer and radiofrequency ablation. J Vasc Interv Radiol. 2006;17:927–951quiz 951.
  4. Gervais DA, Arellano RS, Mueller P. Percutaneous ablation of kidney tumors in nonsurgical candidates. Oncology (Williston Park). 2005;19:6–11
  5. Callstrom MR, Charboneau JW. Percutaneous ablation: Safe, effective treatment of bone tumors. Oncology (Williston Park). 2005;19:22–26
  6. Ahmed M, Goldberg SN. Image-guided tumor ablation: Basic science. In:  vanSonnenberg E,  McMullen W,  Solbiati L editor. Tumor Ablation: Principles and Practice. New York, NY: Springer; 2005;p. 23–40
  7. Hines-Peralta AU, Pirani N, Clegg P, et al. Microwave ablation: Results with a 2.45-GHz applicator in ex vivo bovine and in vivo porcine liver. Radiology. 2006;239:94–102
  8. Yu NC, Lu DS, Raman SS, et al. Hepatocellular carcinoma: Microwave ablation with multiple straight and loop antenna clusters—Pilot comparison with pathologic findings. Radiology. 2006;239:269–275
  9. He W, Hu XD, Wu DF, et al. Ultrasonography-guided percutaneous microwave ablation of peripheral lung cancer. Clin Imaging. 2006;30:234–241
  10. Brace CL, Laeseke PF, Sampson LA, et al. Microwave ablation with a single small-gauge triaxial antenna: In vivo porcine liver model. Radiology. 2007;242:441–449
  11. Kuang M, Lu MD, Xie XY, et al. Liver cancer: Increased microwave delivery to ablation zone with cooled-shaft antenna—Experimental and clinical studies. Radiology. 2007;242:914–924
  12. Duck FA. Physical Properties of Tissue: A Comprehensive Reference Book. London: Academic Press; 1990;
  13. Lu DS, Raman SS, Vodopich DJ, et al. Effect of vessel size on creation of hepatic radiofrequency lesions in pigs: Assessment of the “heat sink” effect. AJR. 2002;178:47–51
  14. Goldberg SN, Solbiati L, Hahn PF, et al. Large-volume tissue ablation with radio frequency by using a clustered, internally cooled electrode technique: Laboratory and clinical experience in liver metastases. Radiology. 1998;209:371–379
  15. LeVeen HH, Wapnick S, Piccone V, et al. Tumor eradication by radiofrequency therapy (Responses in 21 patients). JAMA. 1976;235:2198–2200
  16. Goldberg SN, Gazelle GS, Solbiati L, et al. Radiofrequency tissue ablation: Increased lesion diameter with a perfusion electrode. Acad Radiol. 1996;3:636–644
  17. Tacke J, Mahnken A, Roggan A, et al. Multipolar radiofrequency ablation: First clinical results. Rofo. 2004;176:324–329
  18. Lee FT, Haemmerich D, Wright AS, et al. Multiple probe radiofrequency ablation: Pilot study in an animal model. J Vasc Interv Radiol. 2003;14:1437–1442
  19. Rossi S, Garbagnati F, De Francesco I, et al. Relationship between the shape and size of radiofrequency induced thermal lesions and hepatic vascularization. Tumori. 1999;85:128–132
  20. Hines-Peralta A, Sukhatme V, Regan M, et al. Improved tumor destruction with arsenic trioxide and radiofrequency ablation in three animal models. Radiology. 2006;240:82–89
  21. Yu NC, Raman SS, Kim YJ, et al. “Heat-sink effect” of hepatic veins on microwave coagulation: A porcine pilot study. (abstract) In: Radiological Society of North America Scientific Assembly and Annual Meeting Program. Oak Brook, IL: Radiological Society of North America; 2004;p. 622
  22. Strickland AD, Clegg PJ, Cronin NJ, et al. Experimental study of large-volume microwave ablation in the liver. Br J Surg. 2002;89:1003–1007
  23. Brace CL, Laeseke PF, van der Weide Daniel W, et al. Microwave ablation with a triaxial antenna: Results in ex vivo bovine liver. IEEE Trans Microwave Theory Tech. 2005;53:215–220
  24. Liu Z, Ahmed M, Weinstein Y, et al. Characterization of the RF ablation-induced “oven effect”: The importance of background tissue thermal conductivity on tissue heating. Int J Hyperthermia. 2006;22:327–342
  25. Solazzo SA, Liu Z, Lobo SM, et al. Radiofrequency ablation: Importance of background tissue electrical conductivity—An agar phantom and computer modeling study. Radiology. 2005;236:495–502
  26. Lee JM, Youk JH, Kim YK, et al. Radio-frequency thermal ablation with hypertonic saline solution injection of the lung: Ex vivo and in vivo feasibility studies. Eur Radiol. 2003;13:2540–2547
  27. Gananadha S, Morris DL. Saline infusion markedly reduces impedance and improves efficacy of pulmonary radiofrequency ablation. Cardiovasc Intervent Radiol. 2004;27:361–365
  28. Giorgio A, Tarantino L, de Stefano G, et al. Complications after percutaneous saline-enhanced radiofrequency ablation of liver tumors: 3-year experience with 336 patients at a single center. AJR. 2005;184:207–211
  29. Gillams AR, Lees WR. CT mapping of the distribution of saline during radiofrequency ablation with perfusion electrodes. Cardiovasc Intervent Radiol. 2005;28:476–480
  30. Kim TS, Lim HK, Kim H. Excessive hyperthermic necrosis of a pulmonary lobe after hypertonic saline-enhanced monopolar radiofrequency ablation. Cardiovasc Intervent Radiol. 2006;29:160–163
  31. Furukawa K, Miura T, Kato Y, et al. Microwave coagulation therapy in canine peripheral lung tissue. J Surg Res. 2005;123:245–250
  32. Durick NA, Laeseke PF, Broderick LS, et al. Microwave ablation with triaxial antennas tuned for lung: Results from an in vivo porcine model. Radiology. 2007;in press
  33. Simon CJ, Dupuy DE, Mayo-Smith WW. Microwave ablation: Principles and applications. Radiographics. 2005;25(suppl 1):S69–S83
  34. Gervais DA, McGovern FJ, Arellano RS, et al. Radiofrequency ablation of renal cell carcinoma: Part 1, indications, results, and role in patient management over a 6-year period and ablation of 100 tumors. AJR. 2005;185:64–71
  35. Kigure T, Harada T, Yuri Y, et al. Experimental study of microwave coagulation of a VX-2 carcinoma implanted in rabbit kidney. Int J Urol. 1994;1:23–27
  36. Laeseke PF, Sampson LA, Frey TM, et al. Thermal ablation in kidneys: Microwave ablation with a triaxial antenna results in larger zones of coagulation than RF (Radiological Society of North America Annual Meeting). 2006;SSA02-06.
  37. Davis KW, Choi JJ, Blankenbaker DG. Radiofrequency ablation in the musculoskeletal system. Semin Roentgenol. 2004;39:129–144
  38. Cantwell CP, O'Byrne J, Eustace S. Radiofrequency ablation of osteoid osteoma with cooled probes and impedance-control energy delivery. AJR. 2006;186:S244–S248
  39. Callstrom MR, Atwell TD, Charboneau JW, et al. Painful metastases involving bone: Percutaneous image-guided cryoablation—Prospective trial interim analysis. Radiology. 2006;241:572–580

 The author discloses financial interest (shareholder and consulting salary) in Micrablate, LLC, a developer of microwave ablation technologies.

PII: S0363-0188(07)00077-1

doi: 10.1067/j.cpradiol.2007.10.001

Current Problems in Diagnostic Radiology
Volume 38, Issue 3 , Pages 135-143 , May 2009

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