Current Problems in Diagnostic Radiology
Volume 36, Issue 3 , Pages 124-141 , May 2007

Bone Tumor Mimics: Avoiding Misdiagnosis

  • C. Frank Gould, MD

      Affiliations

    • Naval Aerospace Medical Institute, Pensacola, FL
  • ,
  • Justin Q. Ly, MD

      Affiliations

    • Department of Radiology, Wilford Hall Medical Center, Lackland AFB, TX
    • Corresponding Author InformationReprint requests: Justin Q. Ly, MD, Department of Radiology, Wilford Hall Medical Center, 2200 Bergquist Drive, Suite 1, Lackland AFB, TX 78236-5300.
  • ,
  • Grant E. Lattin Jr, MD

      Affiliations

    • Department of Radiology, David Grant Medical Center, Travis AFB, CA
  • ,
  • Douglas P. Beall, MD

      Affiliations

    • Department of Radiological Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, OK
  • ,
  • Joseph B. Sutcliffe III, MD

      Affiliations

    • Department of Radiology, Brooke Army Medical Center, Fort Sam Houston, TX.

References 

  1. Jung C, Choi YY, Cho S, et al. Symptomatic cortical desmoids detected on knee SPECT. Clin Nucl Med. 2002;27:437–438
  2. Sklar DH, Phillips JJ, Lachman RS. Case report 683. Distal metaphyseal femoral defect (cortical desmoid; distal femoral cortical irregularity). Skeletal Radiol. 1991;20:394–396
  3. Johnson LC, Genner BA, Engh CA, et al. Cortical desmoids. J Bone Joint Surg Am. 1986;50:828–829
  4. Canale ST. In: Campbell’s Operative Orthopaedics. 10th ed.. St. Louis, MO: Mosby; 2003;p. 667
  5. Waldvogel FA, Medoff G, Swartz MN. Osteomyelitis: A review of clinical features, therapeutic considerations, and unusual aspects (third of three parts). N Engl J Med. 1970;282:316–322
  6. Bonakdar-Pour A, Gaines VD. The radiology of osteomyelitis. Orthop Clin North Am. 1983;14:21–37
  7. Marti-Bonmati L, Aparisi F, Poyatos C, et al. Brodie abscess: MR imaging appearance in 10 patients. J Magn Reson Imaging. 1993;3:543–546
  8. Canale ST. In: Campbell’s Operative Orthopaedics. 10th ed.. St. Louis, MO: Mosby; 2003;p. 667
  9. Lee L, Manolios N, De Costa R, et al. Herniation pit of the femoral neck. J Rheumatol. 2000;27:2278–2280
  10. Daenen B, Preidler KW, Padmanabhan S, et al. Symptomatic herniation pits of the femoral neck: anatomic and clinical study. AJR. 1997;168:149–153
  11. Nokes SR, Vogler JB, Spritzer CE, et al. Herniation pits of the femoral neck: Appearance at MR imaging. Radiology. 1989;172:231–234
  12. Grainger RG, Allison D, Adam A, et al. In: Grainger & Allison’s Diagnostic Radiology: A Textbook of Medical Imaging. 4th ed.. Edinburgh: Churchill Livingstone; 2001;p. 2138
  13. Helms CA. Pseudocysts of the humerus. AJR. 1978;131:287–288
  14. White LM, Kandel R. Osteoid-producing tumors of bone. Semin Musculoskelet Radiol. 2000;4:25–43
  15. Murphey MD, Andrews CL, Flemming DJ, et al. From the archives of AFIP: Primary tumors of the spine: radiographic and pathologic correlation. Radiographics. 1996;16:1131–1158
  16. Hall FM, Goldberg RP, Davies JA, et al. Scintigraphic assessment of bone islands. Radiology. 1980;135:737–742
  17. Schajowicz F, Sainz MC, Slullitel JA. Juxta-articular bone cysts (intraosseous ganglia) (A clinicopathological study of eighty-eight cases). J Bone Joint Surg Br. 1979;61:107
  18. Spouge AR, Bell RS. Magnetic resonance imaging of bone tumours and mimics: Pictorial essay. Can Assoc Radiol J. 2003;54:221–233
  19. Stark DD, Genant HK, Spring DB. Primary cystic arthrosis of the hip. Skeletal Radiol. 1984;11:124–127
  20. Biermann JS. Common benign lesions of bone in children and adolescents. J Pediatr Orthop. 2002;22:268–273
  21. Azouz EM. Magnetic resonance imaging of benign bone lesions: Cysts and tumors. Top Magn Reson Imaging. 2002;13:219–229
  22. Spitz DJ, Newberg AH. Imaging of stress fractures in the athlete. Radiol Clin North Am. 2002;40:313–331
  23. Ishibashi Y, Okamura Y, Otsuka H, et al. Comparison of scintigraphy and magnetic resonance imaging for stress injuries of bone. Clin J Sport Med. 2002;12:79–84
  24. Perron AD, Brady WJ, Keats TA. Principles of stress fracture management (The whys and hows of an increasingly common injury). Postgrad Med. 2001;110:115–118123-4
  25. Zwas ST, Elkanovitch R, Frank G. Interpretation and classification of bone scintigraphic findings in stress fractures. J Nucl Med. 1987;28:452–457
  26. Anderson MW, Greenspan A. Stress fractures. Radiology. 1996;199:1–12
  27. Brandser EA, El-Koury GY, Kathol MH. Adolescent hamstring avulsions that simulate tumors. Emerg Radiol. 1995;2:273–278
  28. Tehransadeh J. The spectrum of avulsion and avulsion-like injuries of the musculoskeletal system. Radiographics. 1987;7:945–974
  29. Ecklund K. Magnetic resonance imaging of pediatric musculoskeletal trauma. Top Magn Reson Imaging. 2002;13:203–217
  30. Metzmaker JN, Pappas AM. Avulsion fractures of the pelvis. Am J Sports Med. 1985;12:349–358
  31. States LJ. Pediatric musculoskeletal radiology: Imaging of metabolic bone diseases and marrow disorder in children. Radiol Clin North Am. 2001;39:749–772
  32. Rao VM, Fishman M, Mitchell DG, et al. Painful sickle cell crisis: Bone marrow patterns observed with MR imaging. Radiology. 1986;161:211–215
  33. Koren A, Gart I, Katzuni E. Bone infarction in children with sickle cell disease: Early diagnosis and differentiating from osteomyelitis. Eur J Pediatr. 1984;142:93–97
  34. Parikh J, Hyare H, Saifuddin A. The imaging features of post-traumatic myositis ossificans, with emphasis on MRI. Clin Radiol. 2002;57:1058–1066
  35. Wang SY, Lomasney LM, Demos TC, et al. Radiologic case study (Traumatic myositis ossificans). Orthopedics. 1999;22:1000;991-5
  36. Amendola MA, Glazer GM, Agha FP, et al. Myositis ossificans circumscripta: Computed tomographic diagnosis. Radiology. 1983;149:775–779
  37. De Smet AA, Norris MA, Fisher DR. Magnetic resonance imaging of myositis ossificans: Analysis of seven cases. Skeletal Radiol. 1992;21:503–507
  38. Wang SY, Lomasney LM, Demos TC, et al. Radiologic case study (Traumatic myositis ossificans). Orthopedics. 1999;22:991–9951000
  39. Gindele A, Schwamborn D, Tsironis K, et al. Myositis ossificans traumatica in young children: A report of three cases and a review of the literature. Pediatr Radiol. 2000;30:451–459
  40. Okayama A, Futani H, Kyo F, et al. Usefulness of ultrasonography for early recurrent myositis ossificans. J Orthop Sci. 2003;8:239–242
  41. Polat P, Kantarci M, Alper F, et al. The spectrum of radiographic findings in primary hyperparathyroidism. Clin Imaging. 2002;26:197–205
  42. Doppman JL, Marx S, Spiegel A, et al. Differential diagnosis of brown tumor vs. cystic osteitis by arteriography and computed tomography. Radiology. 1979;131:339–340
  43. Agarwal G, Mishra SK, Kar DK, et al. Recovery pattern of patients with osteitis fibrosa cystica in primary hyperparathyroidism after successful parathyroidectomy. Surgery. 2002;132:1075–1085
  44. Preidler KW, Brossman J, Resnick D. Osteoarthritis. Semin Roentgenol. 1996;31:208–219
  45. Spouge AR, Bell RS. Magnetic resonance imaging of bone tumours and mimics: Pictorial essay. Can Assoc Radiol J. 2003;54:221–233
  46. Bancroft LW, Peterson JJ, Kransdorf MJ. Cysts, geodes, and erosions. Radiol Clin North Am. 2004;41:73–87
  47. Guermazi A, Zaim S, Taouli B, et al. MR findings in knee osteoarthitis. Eur Radiol. 2003;13:1370–1386
  48. Zanetti M, Bruder E, Romero J, et al. Bone marrow edema pattern in osteoarthritic knees: correlation between MR imaging and histologic findings. Radiology. 2000;215:835–840

 The views expressed in this article are those of the authors and do not necessarily represent the official policy or position of the Department of the Air Force, the Department of the Navy, or the United States government.

PII: S0363-0188(07)00002-3

doi: 10.1067/j.cpradiol.2007.01.001

Current Problems in Diagnostic Radiology
Volume 36, Issue 3 , Pages 124-141 , May 2007